Product Name:Oxytetracycline (OTC)
Introduction:Oxytetracycline was the second of the broad-spectrum tetracycline group of antibiotics to be discovered.
Oxytetracycline works by interfering with the ability of bacteria to produce proteins that are essential to them. Without these proteins the bacteria cannot grow, multiply and increase in numbers.
Oxytetracycline is a broad spectrum antibiotic that is active against a wide variety of bacteria. However, some strains of bacteria have developed resistance to this antibiotic, which has reduced its effectiveness for treating some types of infection.
Appearance: beige to light yellow crystalline powder
Molecular formula: C22H24N2O9
Molecular weight: 460.43
CAS Number:79-57-2
Application: Oxytetracycline is used to treat infections caused by chlamydia (e.g. the chest infection psittacosis, the eye infection trachoma, and the genital infection urethritis) and infections caused by mycoplasma organisms (e.g. pneumonia).
Oxytetracycline is also used to treat acne.
Oxytetracycline may also be used to treat other rarer infections, such as those caused by a group of micro-organisms called rickettsiae (e.g. Q fever).
Specification: BP2005/EP5
Test items |
Standard |
Characteristics |
A yellow, crystalline
Powder |
Identification |
Positive |
pH |
2.3 to 2.9 |
Light absorption at 353NM |
270 to 290 |
Specific optical rotation |
-188°to –200° |
Light absorbing impurities at
430NM |
Not more than 0.50 |
Light absorbing impurities at
490NM |
Not more than 0.20 |
Related substances (HPLC) |
Conforms |
Heavy metals |
Not more than 50PPM |
Sulphated ash |
Not more than 0.5% |
Water |
Not more than 2.0% |
Assay (HPLC)
(On the anhydrous substance) |
95.0% to 102.0% |
|